Table 2.
Up-regulated pathways in group H or L compared to group M in GSEA enrichment
Hallmark name | Terma description | Set sizeb | NESc | FDR q value |
---|---|---|---|---|
Epithelial mesenchymal transition§ | Genes defining epithelial-mesenchymal transition, as in wound healing, fibrosis, and metastasis | 198 ‡ | 1.87 ‡ | < 0.002 ‡ |
199 † | 2.25 † | 0 † | ||
UV response DN† | Genes downregulated in response to ultraviolet (UV) radiation | 144 | 1.55 | 0.047 |
aTerm, referred to the MSigDB H (hallmark) term
bSet size, gene set size after restricting to dataset
cNES normalized enrichment score. Group M was set as the control group. Positive NES value indicated up-regulation in groups H or L
†referred to comparison L vs. M
‡referred to comparison H vs. M
§referred to both comparisons