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. 2021 Apr 27;11:9093. doi: 10.1038/s41598-021-88724-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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In vitro study for moesin expression under conditions of high glucose or oxidative stress. Moesin and ezrin mRNA expression did not change under the high glucose condition (a,b). Moesin mRNA expression was upregulated under hydrogen peroxide stimulation (c). Moesin mRNA expression increased in a time-dependent manner under the condition of 100 µM hydrogen peroxide stimulation (e). Ezrin mRNA expression did not change (d,f). The expression of Tgfb1 was enhanced under the condition of hydrogen peroxide stimulation (g). The expression of collagen 1 was also upregulated in the same condition (h).