Table 2.
Preoperative | Postoperative 3 weeks | Postoperative 7 weeks | Postoperative 15 weeks | pa | pb pre vs 3 weeks | pc pre vs 7 weeks | pd pre vs 15 weeks | p value* | |
---|---|---|---|---|---|---|---|---|---|
TBUT | |||||||||
DQS | 13.17 ± 2.26 | 13.64 ± 1.68 | 13.93 ± 1.61 | 14.57 ± 0.96 | 0.023 | 0.734 | 0.351 | 0.014 | 0.011 |
HA | 12.37 ± 1.97 | 12.67 ± 2.25 | 13.16 ± 1.83 | 13.41 ± 1.56 | 0.235 | 0.953 | 0.486 | 0.245 | |
Schirmer’s I test score | |||||||||
DQS | 12.74 ± 2.56 | 13.23 ± 2.93 | 13.22 ± 3.11 | 13.44 ± 3.12 | 0.908 | 0.931 | 0.931 | 0.931 | 0.508 |
HA | 12.04 ± 2.51 | 12.33 ± 2.49 | 13.12 ± 2.84 | 13.00 ± 3.03 | 0.457 | 0.983 | 0.519 | 0.619 | |
OSDI | |||||||||
DQS | 15.24 ± 8.59 | 8.28 ± 5.92 | 7.80 ± 5.81 | 6.36 ± 5.27 | < 0.001 | 0.002 | 0.001 | < 0.001 | 0.009 |
HA | 17.94 ± 7.78 | 12.74 ± 7.77 | 13.16 ± 7.54 | 12.79 ± 7.97 | 0.119 | 0.174 | 0.237 | 0.181 | |
LLT | |||||||||
DQS | 87.78 ± 13.55 | 92.57 ± 10.79 | 92.42 ± 10.80 | 95.96 ± 7.22 | 0.010 | 0.321 | 0.348 | 0.004 | < 0.001 |
HA | 79.21 ± 18.33 | 77.87 ± 20.41 | 79.67 ± 22.59 | 84.96 ± 15.74 | 0.606 | 0.995 | 1.000 | 0.735 |
Statistically significant p values are marked in bold (p < 0.05).
TBUT tear break up time, OSDI ocular surface disease index, LLT lipid layer thickness.
*p value < 0.05 by repeated-measures analysis of variance.
ap value < 0.05 one-way analysis followed by post-hoc Tukey analysis.
bBetween preoperative visit and postoperative 3 weeks.
cBetween preoperative visit and postoperative 7 weeks.
dBetween preoperative visit and postoperative 15 weeks.