Table 2.
Overview of atlases and number of features extracted for regional analysis of morphology, brain iron accumulation/deposition, and microstructural integrity.
| Modality | Type of feature | Atlases used | Total number of extracted features |
|---|---|---|---|
| T1-weighted MRI |
Morphology: Regional Volume (V) Regional Brain Surface (SA) Regional Surface area to Volume Ratio (SA:V) |
Harvard-Oxford Cortical | 234 |
| Harvard-Oxford Sub Cortical | |||
| MNI brain regions | |||
| T2-weighted MRI |
Brain iron content: R2, R2*, R2′ |
Harvard-Oxford Cortical | 396 |
| Harvard-Oxford Sub Cortical | |||
| Johns Hopkins University White Matter Tractography | |||
| Diffusion-tensor MRI |
Microstructural integrity: Mean diffusivity (MD) Fractional anisotropy (FA) Radial diffusivity (RD) Axial diffusivity (AD) |
Harvard-Oxford Cortical | 520 |
| Harvard-Oxford Sub Cortical | |||
| Johns Hopkins University White Matter Tractography |