Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 14;15:604865. doi: 10.3389/fncel.2021.604865

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Cayre, Falque, Mercier, Magalon and Durbec.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Cell sources for myelin regeneration. Following a demyelination insult, oligodendrocyte progenitor cells (OPCs) are mobilized: they proliferate, migrate toward the injury, and finally differentiate into new myelinating oligodendrocytes (OLGs). These OPCs contributing to myelin repair may be derived from the subventricular zone (SVZdOPC) [directly or by reprogramming of neuroblasts (SVZdNB)], from embryo-derived OPCs (pOPC) or from Schwann cells (SCdOPC). Surviving OLG can also produce new myelin segments thus contributing to remyelination.