TABLE 3.

Determinants of susceptibility values in gray matter structures: results of univariate analysis.

		Thalamus			Globus pallidus			Putamen			Caudate nucleus			Red nucleus			Substantia nigra			Dentate nucleus
		Susceptibility	Statistical		Susceptibility	Statistical		Susceptibility	Statistical		Susceptibility	Statistical		Susceptibility	Statistical		Susceptibility	Statistical		Susceptibility	Statistical
		value	value		value	value		value	value		value	value		value	value		value	value		value	value
			t	p		t	p		t	p		t	p		t	p		t	p		t	p
CMBs	No (83)	-1.52 ± 13.60	-2.190	0.031	186.96 ± 48.35	0.476	0.635	95.53 ± 29.41	-2.094	0.039	82.33 ± 22.03	-0.786	0.434	148.94 ± 40.14	-0.301	0.794	159.58 ± 37.54	0.309	0.758	111.47 ± 42.60	0.154	0.878
	Yes (22)	5.89 ± 15.97			181.52 ± 44.77			111.09 ± 36.54			86.67 ± 26.37			152.03 ± 51.92			156.61 ± 48.73			109.95 ± 34.34
WMH	0 (31)	0.20 ± 15.27	0.076	0.940	181.69 ± 43.50	-0.575	0.566	93.74 ± 30.00	-1.064	0.290	83.47 ± 25.15	0.068	0.946	152.68 ± 40.24	0.480	0.632	162.26 ± 38.45	0.548	0.585	109.13 ± 44.13	-0.327	0.744
	1 (74)	-0.03 ± 14.08			187.55 ± 49.21			100.90 ± 32.06			83.14 ± 22.12			148.29 ± 43.78			157.57 ± 40.66			112.00 ± 39.70
Lacunes	0 (89)	-0.49 ± 14.84	-0.893	0.374	187.52 ± 48.55	0.865	0.389	97.49 ± 31.83	-1.000	0.320	83.25 ± 23.08	0.010	0.992	153.17 ± 41.23	2.065	0.041	160.87 ± 38.29	1.163	0.248	112.91 ± 42.36	1.042	0.300
	1 (16)	2.99 ± 11.36			176.36 ± 41.02			106.04 ± 29.43			83.18 ± 22.88			129.64 ± 46.03			148.29 ± 47.88			101.36 ± 30.44
Hypertension	No (46)	2.13 ± 15.85	1.325	0.188	190.74 ± 46.77	0.936	0.351	97.61 ± 30.60	-0.338	0.736	83.78 ± 24.38	0.213	0.831	161.25 ± 36.39	2.541	0.013	165.95 ± 38.43	1.599	0.113	118.90 ± 44.04	1.732	0.086
	Yes (59)	-1.60 ± 13.00			182.00 ± 48.05			99.71 ± 32.41			82.81 ± 21.95			140.49 ± 45.14			153.50 ± 40.49			105.11 ± 37.47
Diabetes	No (82)	-1.33 ± 14.26	-1.858	0.066	186.54 ± 48.46	0.292	0.711	95.54 ± 33.36	-2.024	0.046	80.21 ± 23.18	-2.623	0.010	145.53 ± 43.31	-1.860	0.066	156.87 ± 38.16	-1.014	0.313	106.12 ± 41.18	-2.440	0.016
	Yes (23)	4.90 ± 14.00			183.20 ± 44.64			110.36 ± 23.92			94.02 ± 18.77			164.02 ± 37.45			166.41 ± 45.93			129.10 ± 34.91
Hyperlipidemia	No (73)	-0.15 ± 15.29	-0.199	0.842	190.50 ± 51.98	1.534	0.128	97.64 ± 33.19	-0.565	0.574	82.44 ± 23.92	-0.533	0.595	152.52 ± 42.57	1.029	0.306	161.42 ± 37.99	0.956	0.341	112.35 ± 44.07	0.451	0.653
	Yes (32)	0.46 ± 12.23			175.16 ± 33.38			101.42 ± 27.55			85.04 ± 20.77			143.12 ± 42.69			153.33 ± 44.07			108.42 ± 32.85
E4 gene	No (88)	-0.94 ± 14.05	-1.792	0.076	185.64 ± 48.92	-0.229	0.819	99.30 ± 29.95	-0.274	0.785	83.53 ± 21.37	-0.859	0.392	150.21 ± 41.33	0.208	0.835	159.67 ± 40.66	0.466	0.642	115.12 ± 41.81	1.619	0.109
	Yes (14)	6.48 ± 16.46			188.82 ± 35.75			101.75 ± 37.98			89.00 ± 26.77			147.62 ± 53.22			154.23 ± 40.31			96.36 ± 27.89
Smoke	No (79)	-1.55 ± 12.81	-2.004	0.048	184.30 ± 43.97	-0.572	0.568	95.98 ± 28.33	-1.606	0.111	82.50 ± 20.95	-0.571	0.569	148.68 ± 41.95	-0.379	0.706	157.27 ± 36.68	-0.753	0.453	112.81 ± 43.35	0.725	0.470
	Yes (26)	4.86 ± 17.75			190.46 ± 57.54			107.33 ± 39.00			85.47 ± 28.50			152.34 ± 45.34			164.08 ± 48.88			106.10 ± 32.35
Gender	M (48)	1.49 ± 16.18	0.949	0.345	182.50 ± 52.27	-0.657	0.513	97.19 ± 35.03	-0.476	0.635	81.67 ± 24.39	-0.641	0.523	146.74 ± 40.93	-0.626	0.533	161.60 ± 44.49	0.622	0.533	103.47 ± 41.56	-1.786	0.077
	F (57)	-1.19 ± 12.66			188.62 ± 43.29			100.14 ± 28.43			84.56 ± 21.77			151.98 ± 44.21			156.73 ± 35.84			117.62 ± 39.47

Significant p-values < 0.10 are highlighted in italics. CMBs, cerebral microbleeds; WMH, white matter hyperintensity.