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. 2021 Apr 14;15:604197. doi: 10.3389/fnins.2021.604197

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Copyright © 2021 Belov, Appleton, Levin, Giffenig, Durcanova and Papisov.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Bolus IT injections in rats. (A) The time-dependence curve of ICP elevation. The average administration rate is 2.7 ± 0.9 ml/min. (B) Dependence of the ICP elevation on the injected volume. (C) The pressure dependence of the total ICP elevation (blue) and ICP relaxation time (red).