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. 2020 Nov 9;60(7):977–983. doi: 10.2169/internalmedicine.5648-20

Table 2.

The Expression Patterns of PD-1, CD8, FOXP3 in NENs.

N PD-1 expression CD8 expression FOXP3 expression
Tumorhigh Tumorlow p value Tumorhigh Tumorlow p value Tumorhigh Tumorlow p value
Total 20 7 13 14 6 12 8
WHO grade 0.9819 0.3102 0.8262
G1 2 4 4 2 3 3
G2 3 3 7 1 5 3
NEC 2 4 3 3 4 2
Primary lesion 0.8485 0.1661 0.0404*
Pancreas 4 8 10 2 5 7
Others 3 5 4 4 7 1
PD-L1 expression 0.6392 0.5492 0.6186
Positive 6 10 12 4 9 7
Negative 1 3 2 2 3 1

PD-1: programed death 1, FOXP3: forkhead or winged helix family of transcription factor P3, NENs: neuroendocrine neoplasms

*stands for the value of p<0.05.