Table 2.
The Expression Patterns of PD-1, CD8, FOXP3 in NENs.
N | PD-1 expression | CD8 expression | FOXP3 expression | |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tumorhigh | Tumorlow | p value | Tumorhigh | Tumorlow | p value | Tumorhigh | Tumorlow | p value | ||||||||||||
Total | 20 | 7 | 13 | 14 | 6 | 12 | 8 | |||||||||||||
WHO grade | 0.9819 | 0.3102 | 0.8262 | |||||||||||||||||
G1 | 2 | 4 | 4 | 2 | 3 | 3 | ||||||||||||||
G2 | 3 | 3 | 7 | 1 | 5 | 3 | ||||||||||||||
NEC | 2 | 4 | 3 | 3 | 4 | 2 | ||||||||||||||
Primary lesion | 0.8485 | 0.1661 | 0.0404* | |||||||||||||||||
Pancreas | 4 | 8 | 10 | 2 | 5 | 7 | ||||||||||||||
Others | 3 | 5 | 4 | 4 | 7 | 1 | ||||||||||||||
PD-L1 expression | 0.6392 | 0.5492 | 0.6186 | |||||||||||||||||
Positive | 6 | 10 | 12 | 4 | 9 | 7 | ||||||||||||||
Negative | 1 | 3 | 2 | 2 | 3 | 1 |
PD-1: programed death 1, FOXP3: forkhead or winged helix family of transcription factor P3, NENs: neuroendocrine neoplasms
*stands for the value of p<0.05.