Table 5.
Correlation and simple and multiple linear regression between CCM parameters and CVR-R.
| CVR-R resting | CVR-R deep breathing | |
|---|---|---|
| CNFLa (mm/mm2) | 0.41**; 0.40**/0.40**/0.34** | 0.36**; 0.35**/0.31**/0.32** |
| CNFDa (number/mm2) | 0.31**; 0.36**/0.35**/0.29** | 0.34**; 0.34**/0.30*/0.31* |
| CNBDa (number/mm2) | 0.35 **; 0.34**/0.31*/0.27* | 0.26*; 0.25*/0.21/0.22 |
| Tortuosity coefficienta | -0.14; -0.21 | -0.16; -0.23*/-0.20/-0.21 |
| CNFL/Tortuosity coefficienta | 0.46**; 0.45**/0.47**/0.39** | 0.42**; 0.41**/0.37**/0.38** |
| CNFLb (mm/mm2) | 0.32**; 0.35**/0.39**/0.31** | 0.32**; 0.32**/0.31*/0.31* |
| CNFDb (number/mm2) | 0.28*; 0.33**/0.35**/0.28** | 0.34**; 0.37**/0.34**/0.34** |
| CNBDb (number/mm2) | 0.25*; 0.22 | 0.23*; 0.18 |
| CNFAb (mm2/mm2) | 0.07; 0.04 | 0.03; -0.04 |
| CNFWb (mm/mm2) | -0.17; -0.15 | -0.22; -0.20 |
Spearman’s rank-sum correlation coefficients for all the patients; Coefficients (standardised) of simple regression r, and multiple regression β, β’ for all the patients. β: independent variables were CVR-R, β’: independent variables were CCM markers. About the other explanatory variables, see text. aImage analysis using CCMetrics busing ACCMetrics *p < 0.05, **p < 0.01.
CNFL, corneal nerve fibre length; CNFD, corneal nerve fibre density; CNBD, corneal nerve branch density.