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. 2021 Apr 14;12:659675. doi: 10.3389/fphar.2021.659675

TABLE 2.

Risk of bias assessment for selected studies.

Dion et al. (2004) Awaisu et al. (2012) Kittikraisak et al. (2012) Kastien-Hilka et al. (2017) Saleem et al. (2018) Zarova et al. (2018) Shedrawy et al. (2019)
Risk of bias assessment tool for non-randomized study (RoBANS)
 Selection of participants Low Low Low Low Low Low Low
 Confounding variables Unclear Unclear Unclear Unclear Unclear Unclear Unclear
 Intervention measurement Low Low Low Low Low Low Low
 Blinding of outcome assessment High High High High High High High
 Incomplete outcome data Low Low Low Low Low Low Low
 Selective outcome reporting Low Low Low Low Low Low Low
Newcastle-ottawa quality assessment scale (NOS)
 Selection Representativeness of the exposed cohort * * * * * NA NA
Selection of the non-exposed cohort - - - - - NA NA
Ascertainment of exposure * * * * * NA NA
Outcome of interest was not present at start of study * * * * * NA NA
Comparability Comparability of cohorts on the basis of the design * * * * * NA NA
 Exposure Assessment of outcome - - - - - NA NA
Enough follow-up for outcomes to occur * * * * * NA NA
Non-response rate * * * * * NA NA
 NOS Score Total stars (max 9) 6 6 6 6 6 NA NA