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Numerical simulation results. (a) Assumed relationship between EtCO2 and CBF that is used in the simulation. (b) Absolute BOLD signal as a function of EtCO2. The BOLD signal here indicates the MR signal intensity obtained from the EPI-based T2*-weighted pulse sequence. (c) CVR as a function of basal EtCO2. (d) CVR as a function of ΔEtCO2. α = 0.14, β = 0.91 (Griffeth and Buxton, 2011).
