Table 3.

Uni-variable and multi-variable analyses with logistic regression models for variables associated with failed de-cannulation in tracheotomised patients who succeeded to weaning from mechanical ventilation

Variables	Uni-variable			Multi-variable
	Crude OR	95% CI	P	Adjusted OR	95% CI	P
Age, years	1.04	1.02–1.05	< 0.001	1.04	1.01–1.07	0.019
BMI, kg/m2	0.92	0.87–0.97	0.002	0.82	0.73–0.92	0.001
Suction frequency, per day	1.65	1.50–1.82	< 0.001	1.82	1.55–2.20	< 0.001
PaO2/FiO2 ratio	1.00	0.99–1.00	0.001	0.99	0.99–1.00	0.002
Lactic acid	5.75	3.50–10.03	< 0.001	9.31	3.87–26.35	< 0.001
Underlying malignancy	1.66	1.07–2.61	0.025	5.37	2.04–15.53	0.001
Non-respiratory causes of MV support	2.99	1.90–4.75	< 0.001	5.11	1.84–15.19	0.002
Neurologic disease at weaning from MV	6.05	3.81–9.77	< 0.001	5.11	2.06–13.58	< 0.001
Delirium at weaning from MV	8.80	5.43–14.57	< 0.001	11.13	4.40–31.50	< 0.001
Vasopressor at weaning from MV	4.77	1.95–14.33	0.002	6.89	1.23–51.27	0.039
Post-tracheostomy pneumonia before weaning from MV	2.53	1.60–4.08	< 0.001	5.45	2.04–16.02	0.001

OR adds ratio, CI confidence interval, BMI body mass index, MV mechanical ventilation