Table 3.
Laboratory parameters and lung function tests in the two groups of patients (normal or altered DLCO % of predicted)
| Normal lung function tests (n = 57) | Abnormal lung function tests (n = 37) | All patients (n = 94) | |
|---|---|---|---|
|
Humoral parameters: White blood cells (#/mm3) |
6000 ± 2600 | 6380 ± 2920 | 6170 ± 2730 |
| Granulocytes (#/mm3) | 4400 ± 2600 | 4860 ± 2650 | 4590 ± 2590 |
| Monocytes (#/mm3) | 429 ± 376 | 485 ± 578 | 410 ± 210 |
| Lymphocytes (#/mm3) | 1940 (950) | 2120 (1200) | 2014 (980) |
| Hemoglobin (g/dL) | 13.3 ± 1.6 | 12.3 ± 1.77 ** | 12.9 ± 1.64 |
| Platelets (# × 103/mm3) | 205 ± 72 | 229 ± 99 | 215 ± 84 |
| CRP (mg/L) | 76.1 ± 61.5 | 115.9 ± 94.9 * | 91.8 ± 78.4 |
| Ferritin (µg/L) | 148 (115) | 113 (161) | 141 (142) |
| D-dimer (ng/mL) | 220 ± 80.4 | 398 ± 485 * | 297 ± 332 |
| Creatinine (mg/dL) | 0.94 ± 0.26 | 0.99 ± 0.45 | 0.96 ± 0.35 |
| AST | 52 ± 52 | 44 ± 29 | 49 ± 40 |
| ALT | 43 ± 46 | 32 ± 25 | 39 ± 39 |
| INR | 1.2 ± 0.2 | 1.3 ± 0.3 | 1.3 ± 0.3 |
| aPTT (s) | 33.1 ± 4.3 | 33.0 ± 4.3 | 33.1 ± 4.3 |
| Lung function test | |||
| FVC (L) | 4.1 ± 1.0 | 3.3 ± 0.8*** | 3.8 ± 1.0 |
| FEV1 (L) | 3.2 ± 0.7 | 2.6 ± 0.7*** | 3.0 ± 0.8 |
| DLCO (mL/min/mmHg) | 23.5 ± 5.7 | 15.5 ± 2.8*** | 20.4 ± 6.2 |
| VA (mL/min) | 5.5 ± 1.0 | 4.4 ± 0.9*** | 5.1 ± 1.1 |
| VA % predicted. | 89.5% ± 10.9% | 78.5% ± 15.9%*** | 84.8% ± 14.2% |
| DLCO % predicted | 94.9 ± 14.2 | 66.8 ± 8.6*** | 84.2 ± 18.4 |
| DLCO/VA% predicted (= KCO) | 97.0 ± 20.1 | 82.2 ± 19.3*** | 91.2 ± 21.0 |
| FEV1/FVC | 78.7% ± 7.2% | 78.5% ± 10.9% | 78.6% ± 8.8% |
| DLCO/VA | 4.3 ± 0.6 | 3.6 ± 0.8*** | 4.03 ± 0.8 |