Table 4.

Results of the models from the unimputed datasets.

	GAF symptoms			GAF disabilities
	Coefficient	95% CI	p-value	Coefficient	95% CI	p-value
EUGEI
Patients	−1.50	−2.54 to −0.47	0.005	−1.14	−2.20 to −0.09	0.033
Siblings	−3.17	−3.93 to −2.42	<0.001	−2.82	−3.56 to −2.09	<0.001
Controls	−1.78	−2.20 to −1.35	<0.001	−1.50	−1.88 to −1.11	<0.001
GROUP (replication)a
Patients	−1.39	−2.50 to −0.28	0.014	−1.01	−2.11 to 0.09	0.071

Notes: All analyses were adjusted for age, sex, and education (1 = “No qualification,” 2 = “With qualification (secondary),” 3 = “Tertiary,” 4 = “Vocational,” and 5 = “University”). Analyses in the EUGEI were additionally adjusted for country (Turkey, Spain, and Serbia).

Abbreviations: CI, confidence interval; EUGEI, the European Network of National Networks Studying Gene–Environment Interactions in Schizophrenia; GAF, Global Assessment of Functioning; GROUP, the Genetic Risk and Outcome of Psychosis.

^aThe patient population of the GROUP served as the replication dataset.