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. 2021 Apr 20;2(4):100247. doi: 10.1016/j.xcrm.2021.100247

Figure 2.

Figure 2

Similar-level β-to-βs-globin gene conversion among subpopulations of CD34+ cells

(A) A β-to-βs-globin gene conversion model to evaluate HDR and indels among sorted subpopulations of edited CD34+ cells 2 days post-electroporation.

(B) HDR and indels among subpopulations (CD34+CD133+CD90+, CD34+CD133+CD90−, CD34+CD133−, and CD34−) of edited CD34+ cells. Not significant, evaluated by Dunnett’s test, compared with bulk cells (n = 3). SEM shown as error bars.

(C) HDR and indels among cell cycles (G0/G1, S, and G2/M) in edited CD34+ cells. Not significant, evaluated by Dunnett’s test, compared with bulk cells (n = 3). SEM shown as error bars.