Table 4.
Comparison of demographics and clinical features at baseline between patients with camptocormia and matched pairs groups when the disease duration < 5 years
| Variables | Total | With camptocormia | Matched pairs | P value |
|---|---|---|---|---|
| Number | 92 | 29 | 63 | – |
| Diagnosis (MSA-P/MSA-C) | 50/42 | 17/12 | 33/30 | 0.577 |
| Sex (male/female) | 46/46 | 12/17 | 34/29 | 0.262 |
| Age | 62.30 ± 8.51 | 61.64 ± 7.53 | 62.61 ± 8.96 | 0.542 |
| Age of onset | 59.39 ± 8.47 | 58.63 ± 7.54 | 59.74 ± 8.91 | 0.427 |
| Disease duration | 2.91 ± 1.08 | 3.01 ± 1.01 | 2.87 ± 1.11 | 0.548 |
| Educational year | 10.13 ± 3.92 | 10.69 ± 4.31 | 9.87 ± 3.74 | 0.329 |
| Onset symptoms | ||||
| Autonomic symptom | 36 | 12 | 24 | |
| Cerebellar symptom | 23 | 5 | 18 | 0.488 |
| Parkinsonism symptom | 33 | 12 | 21 | |
| UMSARS-I | 17.99 ± 6.70 | 18.72 ± 7.06 | 17.65 ± 6.56 | 0.495 |
| UMSARS-II | 20.59 ± 7.51 | 21.38 ± 8.65 | 20.22 ± 6.96 | 0.749 |
| UMSARS-IV | 2.58 ± 0.97 | 2.72 ± 1.16 | 2.51 ± 0.88 | 0.375 |
| Total UMSARS score | 41.15 ± 13.93 | 42.83 ± 15.94 | 40.38 ± 12.97 | 0.699 |
| OH (yes/no) | 28/64 | 9/20 | 19/44 | 0.932 |
| Total score of FAB | 14.27 ± 2.87 | 14.59 ± 2.90 | 14.13 ± 2.87 | 0.462 |
| Total MOCA score | 21.59 ± 5.18 | 22.10 ± 5.48 | 21.35 ± 5.07 | 0.365 |
| HDRS score | 12.65 ± 8.40 | 13.24 ± 8.58 | 12.38 ± 8.37 | 0.680 |
| HARS score | 10.41 ± 7.12 | 10.59 ± 6.75 | 10.33 ± 7.34 | 0.893 |
| Disability (yes/no) | 45/47 | 12/17 | 33/30 | 0.327 |
MSA-P multiple system atrophy with predominately parkinsonism, MSA-C multiple system atrophy with predominately cerebellar ataxia, UMSARS unified multiple system atrophy rating scale, OH orthostatic hypotension, FAB frontal lobe battery, MoCA Montreal cognitive assessment, HDRS Hamilton depression rating scale, HARS Hamilton anxiety rating scale