Table 2.
Exacerbation status up to Week 16 by fibrinogen quartile and withdrawal status
| Week 16 fibrinogen data | No Week 16 fibrinogen data | ||||||
|---|---|---|---|---|---|---|---|
| Exacerbation | Quartile 1 N = 2017 |
Quartile 2 N = 2025 |
Quartile 3 N = 2002 |
Quartile 4 N = 2050 |
Withdrewa N = 1195 |
Otherb N = 1066 |
Total N = 10,355 |
| Yes, n (%) | 452 (22) | 476 (24) | 509 (25) | 609 (30) | 547 (46) | 271 (25) | 2864 (28) |
| No, n (%) | 1565 (78) | 1549 (76) | 1493 (75) | 1441 (70) | 648 (54) | 795 (75) | 7491 (72) |
Quartile 1, fibrinogen value < 25th percentile; Quartile 2, fibrinogen value > 25th percentile and < median; Quartile 3, fibrinogen value ≥ median and < 75th percentile; Quartile 4, fibrinogen value ≥ 75th percentile
aPatients who discontinued study treatment/withdrew from the study on or prior to Week 16 and did not have a fibrinogen result at Week 16;
bPatients who did not discontinue study treatment/withdraw from the study on or prior to Week 16 but had a missing fibrinogen result at Week 16