Table 2.
Experiment | n | Region | Age |
---|---|---|---|
qPCR | WT = 4F, 1b+/− = 5 (4F, 1 M), 1b−/− = 7 (2F, 5 M) |
Cortex Hippocampus Cerebellum |
3 months |
Western blot | WT = 3 M, 1b+/− = 3 M, 1b−/− = 3 M |
Cortex Hippocampus Cerebellum |
P29-P32 |
IF | WT = 3, 1b+/− = 3, 1b−/− = 3 | Brain | P28 |
RNA-seq | WT = 2 M, 1b+/− = 4 (2 M, 2F), 1b−/− = 2F | Forebrain | P7 |
WT = 2F, 1b−/− = 2 (1 M, 1F); WT = 3 M, 1b+/− = 4 (3 M, 1F) | Hippocampus | P32 | |
Behavior | WT = 26(12 M, 14F), 1b+/− = 30(15 M, 15F), 1b−/− = 12 (6 M, 6F) | Started at 6 weeks | |
Thermal-induced seizures | WT = 9(5 M, 4F)1b+/− = 9 (6 M, 3F) | P22 |