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. 2021 Apr 27;22:24. doi: 10.1186/s12860-021-00365-7

Fig. 4.

Fig. 4

Akt inhibition suppressed osteogenesis while Akt activation promoted osteogenesis. a and b Relative protein levels of Akt, GSK3β, and β-catenin in BMSCs after different treatments including HG, 740Y-P, LY294002, and GluOC. c Expressions of osteogenic genes RUNX2, OSX, ALP, and adipogenic genes FAS and Ap2. *P < 0.05, **P < 0.01 versus NG; #P < 0.05, ##P < 0.01 versus HG; &P < 0.05, &&P < 0.01 versus HG + GluOC