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. 2021 Apr 28;22:132. doi: 10.1186/s12931-021-01729-5

Table 4.

Clinical features of patients with Pseudomonas aeruginosa colonization

Clinical features of patients with Pseudomonas aeruginosa colonization Univariate analysis Odd ratios and 95% CI p values Multivariate analysis p value
Sputum volume 1.041 (1.024–1.058)  < 0.001
More than 3 lobes of lung involved* 3.869 (2.350–6.369) 0.001 2.445 (1.283–4.657) 0.007
Dyspnoea 2.673 (1.525–4.685) 0.001
Lower FEV1 1.034 (1.020–1.047) 0.001
Lower FVC 1.031 (1.016–1.047)  < 0.001
Lower FEV1/FVC 1.031 (1.010–1.053) 0.004
Risk of all exacerbations 4.778 (2.818–8.103)  < 0.001
Risk of exacerbations requiring hospitalizations* 4.772 (2.393–9.516)  < 0.001 2.745 (1.012–7.449) 0.047

*Factors that are statistically significant after adjustment for FACED score components—FEV1, age, extent of involvement and dyspnea