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. 2021 Apr 27;22:394. doi: 10.1186/s12891-021-04272-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Age-related decline in BMD and Gal-1 levels in peripheral blood serum and the correlation between BMD and serum Gal-1 levels in men of different ages. DEXA was employed to measure BMD of femoral neck (a), total hip (b) and L1-L4 lumbar spine (c) of men within various age groups. ELISA was used to measure Gal-1 levels in peripheral blood serum from these men (d). The correlation of serum Gal-1 levels with BMD was analyzed (e, f and g). FN: femoral neck, TH: total hip, BMD: bone mineral density. Data were shown as the means ± SD. *: p < 0.05, **: p < 0.01, ***: p < 0.001