Table 1.
Characteristics of the study patients.
| Number of patients (%) | |
|---|---|
| Characteristics on inclusion | |
| Gender | |
| Male | 55 (76) |
| Female | 17 (24) |
| Smoking status | |
| Never a smoker | 36 (56) |
| Former smoker | 21 (32) |
| Currently a smoker | 8 (12) |
| Acute phase management | |
| Intensive care unit | 54 (76) |
| Intensive care unit admission | |
| PaO2/FiO2 (mmHg/FiO2) | 109 [88; 148] |
| HFO | 18 (34) |
| Non-invasive ventilation | 13 (24) |
| Use of curare | 33 (65) |
| Mechanical ventilation | 37 (68) |
| Prone positioning | 29 (54) |
| Use of nitric oxide | 5 (9) |
| ECMO | 3 (6) |
| Extrarenal purification | 4 (7) |
| Drug therapies | |
| Corticosteroids | 26 (36) |
| Hydroxychloroquine | 38 (53) |
| Azithromycin | 1 (1) |
| Ritonavir/lopinavir | 8 (11) |
| Remdesivir | 8 (11) |
| Antibiotics | 68 (94) |
| Curative anticoagulation | 27 (37) |
| Complications | |
| Bacterial pneumonia | 36 (51) |
| Fungal infection | 3 (4) |
| Venous thromboembolism | 23 (32) |
| Pulmonary embolism | 18 (25) |
| Deep vein thrombosis | 9 (12) |
| ARDS | 41 (57) |
| Myocarditis | 1 (1) |
| Post-intensive care tetraparesis | 16 (22) |
| Baseline CT abnormalities | |
| Mild (< 10%) | 6 (9) |
| Moderate (10–25%) | 16 (25) |
| Extensive (25–50%) | 20 (31) |
| Severe (50–75%) | 17 (26) |
| Critical (> 75%) | 6 (9) |
PaO2/FiO2: ratio of arterial oxygen partial pressure to fractional inspired oxygen; HFO: high-flow oxygen; ECMO: extracorporeal membrane oxygenation; ARDS: acute respiratory distress syndrome.