Table 2.
List of existing and nascent single-cell genomics consortiums.
| Consortium | Short name | Mission | Website | Funding source |
|---|---|---|---|---|
| The Human Cell Atlas | HCA | To create comprehensive reference maps of all human cells as a basis for both understanding human health and diagnosing, monitoring, and treating disease | https://www.humancellatlas.org/ | Variousa |
| Human Biomolecular Atlas Program | HuMAP | To develop an open and global platform to map healthy cells in the human body | https://hubmapconsortium.org/ | NIH |
| Gene-Tissue Expression | GTEx | To build a comprehensive public resource to study tissue-specific gene expression and regulation | https://gtexportal.org/ | NIH |
| LifeTime Initiative | LifeTime | Revolutionizing healthcare by tracking, understanding, and treating human cells during diseases | https://lifetime-fetflagship.eu/ | EU (Horizon 2020) |
| The Human Protein Atlas | HPA | To map all the human proteins in cells, tissues, and organs using integration of various omics technologies, including antibody-based imaging, mass spectrometry-based proteomics, transcriptomics, and systems biology | https://www.proteinatlas.org/ | Knut and Alice Wallenberg Foundation (main) |
| Single-cell eQTLGen Consortium | sc-eQTLGen | To identify the upstream interactors and downstream consequences of trait-related genetic variants in specific immune cell types | https://www.eqtlgen.org/single-cell.html | Various |
| The Human Tumor Cell Atlas | HTCA | Constructing three-dimensional atlases of the cellular, morphological, and molecular features of human cancers over time | https://humantumoratlas.org/ | NIH/NCI |
| Allen Brain Atlas | Allen Brain Map | Accelerating progress toward understanding the brain | https://portal.brain-map.org/ | Philanthropic (Paul G. Allen) |
| The BRAIN initiative | Cell Census Network (BICCN) | Discovering diversity: identify and provide experimental access to the different brain cell types to determine their roles in health and disease | https://braininitiative.nih.gov/ | NIH |
| The Molecular Atlas of Lung Development Program | LungMAP | Omics, images, 3D viewer, and Analytics platform to study the human lung | https://lungmap.net/ | NHLBI |
| Kidney Precision Medicine Program | KPMP | Purpose of understanding and finding new ways to treat chronic kidney disease (CKD) and acute kidney injury (AKI) | https://kpmp.org/ | NIDDK |
| Immunological Genome Project | ImmGen | To computationally reconstruct the gene- regulatory network in immune cells | http://www.immgen.org/ | NIAID |
| GenitoUrinary Development Molecular Anatomy Project | GUDMAP | Focused on the kidney, lower urinary tract, and nociceptors (pain receptors), and expanding our understanding of human development of the genito-urinary system | https://www.gudmap.org/ | NIDDK |
NIH National Institute of Health, NHLBI National Heart, Lung, and Blood Institute, NIDDK National Institute of Diabetes and Digestive Kidney Diseases, NIAID National Institute of Allergy and Infectious Diseases.
Various: Supported by individual funds.
aInfrastructure support by Chan Zuckerberg Initiative (CZI) https://chanzuckerberg.com/.