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. 2020 Dec 1;52(12):1879–1890. doi: 10.1038/s12276-020-00532-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Subareas within the VTA, in the lateral part of the VTA, the parabrachial pigmented area (PBP), which is continuous with the rostral SN (substantia nigra), and the paranigral nucleus (PN), which is rather restricted to the caudal VTA, are shown, and these regions are rich in DA neurons. The interfacial nucleus (IF) is found in the medial part of the VTA, the rostral linear nucleus of the raphe (RLi) is located in the rostral part of the VTA, and the caudal linear nucleus (CLi) is found in the caudal part of the VTA. The medial (Me) and lateral (L) parts of the VTA are indicated. b Schematic illustration of the NAc. The core and the shell (the medial and lateral parts of the shell are represented by (Me) and (L), respectively) of the NAc are showed together with the ventral pallidum (VP). DAergic neurons in the medial VTA (IF, PN, and medial PBP), which are schematically represented here by green projections, selectively project to the medial shell and core of the NAc, while DAergic neurons in the lateral VTA (lateral PBP), represented as pink projections, project to the lateral (L) shell of the NAc.