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. 2021 Apr 28;11:9168. doi: 10.1038/s41598-021-88392-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Pathway analysis of changed genes between MG and GC, and MG and AG, and identifying novel candidate genes involved in muscle atrophy. (A) Venn diagram showing the number of upregulated (upper) and downregulated (lower) DEGs in each comparison between MG, GC, and AG. (B) Pathway analysis of upregulated (upper) and downregulated (lower) DEGs in the overlapping region of MG compared with GC and AG. (C) Tissue expression profiles of 418 upregulated DEGs in MG compared with AG. (D) The gene list showing skeletal muscle-related genes from Fig. 4C.