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. 2021 Feb 5;53(2):223–234. doi: 10.1038/s12276-021-00559-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Heatmap with intensity and extent depending on the location of the expression of CXCL11. b Representative photomicrographs showing the expression of CXCL11 in gastric cancer tissue. Expression in the tumor cell cytoplasm (top; original magnification ×400), peritumoral vasculature (top, left; original magnification ×400), tumor-infiltrating lymphocytes (middle, right; original magnification ×400), peritumoral stroma (bottom, left; original magnification ×200), and tumor cell membrane (bottom, right; original magnification ×400). c Forest plot of the odds ratio of the expression location of CXCL11. d Progression-free survival using the expression of CXCL11. e Overall survival using the expression of CXCL11. R, responder; NR, nonresponder; ICI, immune checkpoint inhibitor; IHC, immunohistochemistry; CPS, combined positive score; N/A, not available. *P < 0.05 and **P < 0.01, as determined by multivariate logistic regression analysis.