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. 2021 Apr 28;11:9165. doi: 10.1038/s41598-021-87918-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Top four microRNAs associated with AKI for all toxic agents. Violin plots show these microRNAs having increased abundance with increasing AKI severity in all four toxins. Blue lines indicate the medians and each black dot presents a different sample from validation cohort. The y-axis is relative abundance from the detectable limit (2^(39-Ct), Ct of 39 is the threshold of detectability). MicroRNA expressions were normalised using two spike control ath-microRNAs (ath-miR-159a and ath-miR-172a). p is the alternative p value from Jonckheere–Terpstra nonparametric ordered test.