Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 28;12(5):419. doi: 10.1038/s41419-021-03695-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — A Whole chromosome or large partial chromosome gains of chromosomes 7, 5, 13 and 20 were observed in the RC-K8 cell line. B Balanced translocation identified by WGS, involving EP300 on chromosomal 22 and BCKDHB on chromosomal 6, which resulted in a C-terminal truncated form of the protein. C Reads per exon kilobase per million (RPKM) values-based expression analysis of EP300 in RC-K8 by RNA-seq. The expression of the truncated EP300 gene (exons 1–17) was dominant as compared to the full-length gene.