Skip to main content
. 2020 Jul 17;52(7):1128–1139. doi: 10.1038/s12276-020-0469-y

Fig. 3. The effect of FMT and dietary modification on emphysema (Experiment 3).

Fig. 3

a Representative H&E-stained lung tissues from mice in the control, emphysema, emphysema with FMT, emphysema with high-fiber diet, and emphysema with both FMT and high-fiber diet groups (magnification: 100×). b The MLI of lung tissues from each group. c, d The levels of IL-6 and IFN-γ cytokines in the BALF (c) and serum (d) measured using ELISA. e The relative mRNA levels of IL-1β, TNF-α, IFN-γ, IL-6, MMP-12, IRF-5, and Cathepsin S in the lung tissue. f Representative TUNEL images of lung tissue from mice in the control, emphysema, emphysema with FMT, emphysema with high-fiber diet, and emphysema with both FMT and high-fiber diet groups. g TUNEL score (%) of each group. TUNEL score (%) = TUNEL cells × 100/total cells (n = 6 mice per group; n = 4 control mice for IFN-γ and IL-6 analysis in BALF and serum). Values are expressed as the mean ± SE. *P < 0.05 and **P < 0.01. CTL control, E emphysema, FMT fecal microbial transplantation.