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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Hear Res. 2021 Feb 21;404:108216. doi: 10.1016/j.heares.2021.108216

Figure 8.

Figure 8.

ECAP AGFs on the final day tested for all electrodes for two mice (top panel, a) and the primary electrode for multiple guinea pigs of varying cochlear health (middle panel, b). AGF slopes for the primary electrode have been plotted as a function of average SGN density for histology Profiles A through C (bottom panel, c) to show how these two mice have similar slopes to guinea pigs of comparable cochlear health; slope for guinea pigs with good cochlear health can range from around 6 - 22 μV/μA (the guinea pig setting the upper value for this range is still being tested and therefore not shown here). Slopes for each mouse represent the average slope of the two growth functions measured on 42 DPI for electrode 1 and slopes for each guinea pig represent the mean slopes of multiple growth functions obtained during a period when slopes were relatively stable over time (150 DPI to euthanasia) for the primary electrode. Individual symbols are specified for each mouse and circles for guinea pigs. Colors were coded by SGN for panels a and b and IHC survival in Profiles A through C for panel c; red = high, yellow = medium to low, and black = low SGN and no IHC survival.