Table 5.
Change in AIS Grade from Baseline to Follow-Up Assessment for Individuals with Initial AIS B Injuries (Heterogeneous Sample Including Tetraplegia and Paraplegia)
| Authors/year | NLI | Baseline exam | Follow-up exam | Sample size (N) | AIS B to AIS A (%) | Remained AIS B (%) | AIS B to AIS C (%) | AIS B to AIS D (%) | AIS B to AIS E (%) |
|---|---|---|---|---|---|---|---|---|---|
| 8Marino et al. 1999a | All levels | ≤7 d | 1 y | 129 | 7.8 | 19.4 | 5.8 | 2.3 | 0 |
| 47Burns et al. 2003 | All levels | ≤48 h | 1 y | 15 | 0 | 40 | 40 | 20 | 0 |
| 20Spiess et al. 2009b | All levels | ≤15 d | 1 y | 40 | 10.0 | 22.5 | 35 | 32.5 | 0 |
| Above T10 | 10 | 20 | 30 | 20 | 30 | 0 | |||
| 58Kirshblum et al. 2011a | All levels | Discharge (mean 97 d) | 1 y | 269 | 12.6 | 52.0 | 23.1 | 11.5 | 0.7 |
| 21Kirshblum et al. 2016a | All levels | ≤ 30 d | 1 y | 56 | 10.7 | 35.7 | 32.2 | 21.4 | 0 |
| C1-–C8 | 35 | 11.4 | 40 | 25.7 | 22.9 | 0 | |||
| T1–T9 | 8 | 0 | 25.0 | 37.5 | 37.5 | 0 | |||
| T10 and below | 13 | 15.4 | 30.8 | 46.1 | 7.7 | 0 | |||
| 39Marino et al. 2011a | Cervical levels | ≤7 d | 1 y | 125 | 8.8 | 24.8 | 29.6 | 36.8 | 0 |
| 35Waters et al. 1992 | T1–L3 | ≤30 d | Within 2 y | 15 | 26.7% | 26.7% | 46.7% | ||
| 48van Middendorp et al. 2009b | Above T11 | ≤15 d | 6 m–1 y | 37 | 5.4 | 21.6 | 35.1 | 35.1 | 2.7 |
| 62Harrop et al. 2011b | T4–T9 | ≤24 h | 1 y | 3 | 33.3 | 0 | 66.7 | 0 | 0 |
| T10–T12 | 2 | 0 | 100 | 0 | 0 | 0 | |||
| L1 and below | 4 | 0 | 0 | 50 | 25 | 25 | |||
| 61Lee et al. 2016a | T2–T12 | ≤7 d | 1 y | 34 | 20.6 | 20.6 | 26.5 | 29.4 | 2.9 |
| 74Wilson et al. 2018c | T1–L1 | ≤7 d | 6 m - 1 y | 6 | 16.7 | 16.7 | 33.3 | 16.7 | 16.7 |
NLI, Neurological level of injury; AIS, American Spinal Injury Association Impairment Scale.
a
Spinal Cord Injury Model Systems database.
b
European Multicenter Study about Spinal Cord Injury database.
c
North American Clinical Trials Network registry.