Table 6.

Change in AIS Grade from Baseline to Follow-Up Assessment for Individuals with Initial Motor Incomplete Injuries (Sample Including Tetraplegia and Paraplegia)

Authors/year	NLI	Baseline exam	Follow-up exam	Initial AIS	Sample size (N)	AIS A at follow-up (%)	AIS B at follow-up (%)	AIS C at follow-up (%)	AIS D at follow-up (%)	AIS E at follow-up (%)
8Marino et al. 1999a	All levels	≤7 days	1 y	C	159	3.1	1.3	25.1	66.7	3.8
				D	72	0	0	1.4	94.4	4.2
20Spiess et al. 2009b	All levels	≤15 d	1 y	C	46	4.3	0	10.9	84.8	0
				D	49	0	1.7	0	89.8	8.5
	Above T10			C	9	0	0	22	78	0
				D	9	0	0	0	100	0
48van Middendorp et al. 2009b	Above T11	≤15 d	6 m–1 y	C	43	2.3	0	23.3	74.4	0
				D	32	0	0	0	84.4	15.6
21Kirshblum et al. 2016a	All levels (tetraplegia + paraplegia)	≤30 d	1 y	C	109	1.8	6.4	19.3	72.5	0
				D	123	0	0	0	100	0
	Tetraplegia			C	78	1.3	5.1	16.7	76.9	0
				D	94	0	0	0	100	0
	T1–T9			C	11	0	9.1	27.3	63.6	0
	T10 and below				20	5	10	25	60	0
	T1–T9			D	10	0	0	0	100	0
	T10 and below				19	0	0	0	100	0
62Harrop et al. 2011c	T4–T9	≤24 h	1 y	C	5	0	0	20	40	40
	T10–12				2	0	0	0	100	0
	L1 and below				6	0	0	16.7	66.7	16.7
	T4–T9			D	2	0	0	0	0	100
	T10–12				4	0	0	0	25	75
	L1 and below				15	0	0	0	0	100
39Marino et al. 2011a	Tetraplegia	≤7 d	1 y	C	109	0.9	2.8	13.8	80.7	1.8
				D	135	0	0.7	0.7	84.4	14.1
74Wilson et al. 2018d	T1–L1	≤7 d	6 m–1 y	C	8	0	0	0	50	50
				D	3	0	0	0	67.7	33.3
61Lee et al. 2016a	T2–T12	≤7 d	1 y	C	21	0	9.5	4.8	81.0	4.8
				D	16	0	0	0	87.5	12.5

Bolded lines represent all levels, with subdivisions of that study listed below.

NLI, neurological level of injury; AIS, American Spinal Injury Association Impairment Scale.

^aSpinal Cord Injury Model Systems database.

^bEuropean Multicenter Study about Spinal Cord Injury database.

^cSygen database.

^dNorth American Clinical Trials Network registry.