Table 1.
Demographic and Clinical Characteristics in Preeclampsia and Normotensive Control Pregnancies
| Demographic and clinical characteristics | Normotensive controls (N = 23) | Preeclampsia (N = 30) | p |
|---|---|---|---|
| Maternal age (years) | 33.5 ± 2.4 | 34.0 ± 6.6 | 0.7 |
| Race/ethnicity, n (%) | |||
| White/non-Hispanic | 10 (53) | 12 (41) | 0.8 |
| Hispanic/Latin | 4 (21) | 8 (28) | 0.4 |
| Asian/Pacific Islander | 5 (17) | 4 (14) | 0.4 |
| Other | 0 | 5 (17) | |
| Marital status, n (%) | |||
| Married | 17 (94) | 21 (72) | 0.8 |
| Single | 1 (6) | 8 (28) | 0.03 |
| Education (years) | 16.0 ± 1.6 | 14.6 ± 2.4 | 0.02 |
| Gravida, n (%) | |||
| G1 | 10 (43) | 13 (43) | 1.0 |
| G ≥ 2 | 9 (39) | 9 (30) | 0.5 |
| Prepregnancy BMI (kg/m2) | 22.7 ± 3.9 | 27.3 ± 5.3 | 0.001 |
| Gestational diabetes, n (%) | 1 (5) | 7 (24) | 0.06 |
| IVF, n (%) | 0 | 5 (17) | 0.04 |
| Multiparity, n (%) | 2 (11) | 6 (21) | 0.3 |
| Medication use in the third trimester, n (%) | |||
| Antihypertensivesa | 0 | 16 (73) | <0.001 |
| Magnesium sulfate | 1 (5) | 22 (75) | <0.001 |
| Preterm delivery | 2 (11) | 16 (55) | <0.001 |
| Infant gestational age at delivery (weeks) | 39 ± 2 | 35 ± 4 | <0.001 |
| Infant weight at delivery (g) | 3410.2 ± 887.6 | 2437.0 ± 811.5 | <0.001 |
| Systolic blood pressure (mmHg) | 111 ± 10 | 128 ± 12 | <0.001 |
| Diastolic blood pressure (mmHg) | 66 ± 7 | 77 ± 10 | <0.001 |
a
Antihypertensives include labetalol, nifedipine, hydralazine, and metoprolol.
BMI, body mass index; IVF, in vitro fertilization.