Table 1.
Demographics of Transgender and Cisgender Participants
| |
Assigned female at birth |
Assigned male at birth |
||
|---|---|---|---|---|
| Transgender males (n=9) | Cisgender females (n=14) | Transgender females (n=8) | Cisgender males (n=17) | |
| Age (years) | 13.8±1.7 | 13.9±1.7 | 13.7±1.2 | 13.9±0.9 |
| Age at initiation of GnRHa (years) | 12.1±1.9 | — | 12.8±1.3 | — |
| GnRHa duration (months) | 20.9±19.8 | — | 11.3±7 | — |
| Race | ||||
| White | 6 (67) | 10 (71) | 7 (88) | 13 (76) |
| Asian | 0 (0) | 1 (7) | 0 (0) | 1 (6) |
| African American | 1 (11) | 3 (21) | 0 (0) | 1 (6) |
| More than one race | 1 (11) | 0 (0) | 1 (12) | 0 (0) |
| Unknown/not reported | 1 (11) | 0 (0) | 0 (0) | 2 (12) |
| Ethnicity | ||||
| Hispanic/Latino | 4 (44) | 4 (29) | 4 (50) | 3 (18) |
| Not Hispanic/Latino | 5 (56) | 9 (64) | 4 (50) | 13 (76) |
| Unknown/not reported | 0 (0) | 1 (7) | 0 (0) | 1 (6) |
| Depression | 2 (22) | — | 3 (38) | — |
| Anxiety | 1 (11) | — | 1 (12) | — |
| Pubic hair Tanner stage | ||||
| 1 | 1 (11) | 1 (7) | 1 (12) | 1 (6) |
| 2 | 0 (0) | 0 (0) | 3 (38) | 5 (29) |
| 3 | 1 (11) | 2 (14) | 0 (0) | 3 (18) |
| 4 | 3 (33) | 4 (29) | 1 (12) | 2 (12) |
| 5 | 2 (22) | 1 (7) | 1 (12) | 1 (6) |
| Missing | 2 (22) | 6 (43) | 2 (25) | 5 (29) |
| Breast/testicular Tanner stage | ||||
| 2 | 1 (11) | 1 (7) | 5 (63) | 7 (41) |
| 3 | 3 (33) | 1 (7) | 0 (0) | 3 (18) |
| 4 | 2 (22) | 3 (21) | 1 (12) | 3 (18) |
| 5 | 2 (22) | 9 (64) | 2 (25) | 4 (24) |
| Missing | 1 (11) | 0 (0) | 0 (0) | 0 (0) |
| Family historya | ||||
| Hypertension | 5 (63) | 6 (75) | 5 (63) | 9 (75) |
| Hypercholesterolemia | 5 (63) | 7 (88) | 3 (38) | 8 (67) |
| Type 2 diabetes | 4 (50) | 7 (64) | 1 (13) | 4 (33) |
Values above represent the entire cohort used and are either presented as mean±SD or n (%).
a
Family history is given out of total number of reported values (nonmissing). For transgender males, family history was missing for one participant. For cisgender females, family history was missing for hypertension (n=6), hypercholesterolemia (n=6), type 2 diabetes (n=3). Family history was not missing for any transgender female and was missing for 5 cisgender males (all conditions).
GnRHa, gonadotropin-releasing hormone agonist; SD, standard deviation.