Table 1.
Changes in Inflammatory Markers One Week After the Intervention
| Variable | Intervention |
Comparison of changes |
||||
|---|---|---|---|---|---|---|
| Placebo (n = 33) |
B-TURMACTIVE® (n = 35) |
B-TURMACTIVE vs. placebo |
||||
| Baseline (mean ± SD) | One week (mean ± SD) | Baseline (mean ± SD) | One week (mean ± SD) | Mean (95% CI) | P | |
| hsCRP, mg/dL (log) | −0.99 ± 0.36 | −0.96 ± 0.36 | −0.93 ± 0.40 | −1.00 ± 0.41* | −0.104 (−0.21 to −0.001) | .048 |
| IL-1β, pg/mL (log) | 1.40 ± 0.25 | 1.48 ± 0.22** | 1.34 ± 0.3024 | 1.39 ± 0.24 | −0.035 (−0.15 to 0.08) | .532 |
| IL-6, pg/mL (log) | 0.008 ± 0.23 | 0.056 ± 0.34 | 0.004 ± 0.36 | 0.010 ± 0.35 | −0.001 (−0.13 to 013) | .994 |
*
P = .045 and **P = .010 versus baseline.
Variables log transformed for reaching parametricity. ANCOVA model adjusted by sex and age.
95% CI, confidence interval at 95%; ANCOVA, analysis of covariance; hsCRP, high-sensitivity C-reactive protein; IL, interleukin; SD, standard deviation.