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. Author manuscript; available in PMC: 2021 Jul 27.
Published in final edited form as: Nature. 2021 Jan 27;591(7849):300–305. doi: 10.1038/s41586-021-03231-w

Extended Data Figure 8. RNA-seq analysis reveals enhanced mTOR, Myc and glycolytic signatures in TGF-β-induced Aim2–/– Tregs.

Extended Data Figure 8.

a, Heatmap of PI3K-Akt-mTORC related gene expression in WT and Aim2–/– CD4+ T cells stimulated with anti-CD3/CD28 in the presence of TGF-β (2 ng/ml) and IL-2 (40 U/ml) for 24 hr.

b, Heatmap of mTORC1 signaling related gene expression, with samples described in (a). c, Heatmap of Myc targets related gene expression, with samples described in (a). d, Heatmap of glycolysis related gene expression, with samples described in (a).