Figure 5. Adoptive transfer of normal macrophages into knockout mice restores wild-type fibrotic phenotype.

A.Representative 20X sections with Haematoxylin and eosin, Masson’s trichrome, and Picrosirius red stains of LysM-Cre/Tgfb1fl/fl animals 7 days after IR/CTX injury with or without adoptive transfer of LysMCremTmG macrophages. B. Immunofluorescence imaging of positive GFP expression within LysM-Cre/Tgfb1fl/fl muscle 7 days after adoptive transfer.