Table 3. Elastic Net regression model optimal alpha parameters and performance of proteins associated with change in growth deficits within 60 days.
| EN Variable | Optimal
alpha |
r | [95% CI] | P value | |
|---|---|---|---|---|---|
| DWAD | Exposure
protein variables |
0.5 | 0.51 | 0.34 – 0.64 | <0.0001 |
| DMAD | Exposure
protein variables |
0.5 | 0.57 | 0.41 – 0.69 | <0.0001 |
Footnote: Optimal alpha parameter and correlation coefficients for the EN model enumerating the correlation between DWAD and DMAD at two months and exposure protein variables (untargeted plasma proteome, and targeted cytokine/chemokines, leptin, and sCD14) extracted by the multivariate regularized models.
EN = elastic net, DWAD = change in absolute deficits in weight, DMAD = change in absolute deficits in mid-upper-arm circumference, CI = confidence interval.