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. 2021 Mar 16;5:248. Originally published 2020 Oct 22. [Version 2] doi: 10.12688/wellcomeopenres.16330.2

Table 3. Elastic Net regression model optimal alpha parameters and performance of proteins associated with change in growth deficits within 60 days.

EN Variable Optimal
alpha
r [95% CI] P value
DWAD Exposure
protein
variables
0.5 0.51 0.34 – 0.64 <0.0001
DMAD Exposure
protein
variables
0.5 0.57 0.41 – 0.69 <0.0001

Footnote: Optimal alpha parameter and correlation coefficients for the EN model enumerating the correlation between DWAD and DMAD at two months and exposure protein variables (untargeted plasma proteome, and targeted cytokine/chemokines, leptin, and sCD14) extracted by the multivariate regularized models.

EN = elastic net, DWAD = change in absolute deficits in weight, DMAD = change in absolute deficits in mid-upper-arm circumference, CI = confidence interval.