Table 1.
Conjugation sites identified by peptide mapping
| Label | Peptide | Chain | Position |
Relative Population | |
|---|---|---|---|---|---|
| Start | End | ||||
| HC N-term | EVQLVESGGGLVQPGGSLR | HC | 1 | 19 | 45.7% |
| LC N-term | DIQMTQSPSSLSASVGDR | LC | 1 | 18 | 28.5% |
| HC:249 or 251 | THTCPPCPAPELLGGPSVFLFPPKPK | HC | 226 | 251 | 16.8% |
| Others | VYACEVTHQGLSSPVTK | LC | 191 | 207 | 9.1% |
| VDNALQSGNSQESVTEQDSK | LC | 150 | 169 | ||
| VQWK | LC | 146 | 149 | ||
| ASQDVNTAVAWYQQKPGK | LC | 25 | 42 | ||
| GPSVFPLAPSSK | HC | 125 | 136 | ||
| TKPR | HC | 292 | 295 | ||
| VEIK | LC | 104 | 107 | ||
| KVEPK | HC | 217 | 221 | ||
| VSNK | HC | 326 | 329 | ||
| ADYEK | LC | 184 | 188 | ||
| ALPAPIEK | HC | 330 | 337 | ||
| VDK | HC | 214 | 216 | ||
Bold: conjugation site