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. 2021 Apr 27;12(1):1258–1270. doi: 10.1080/21505594.2021.1920762

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Many identified H. pylori genes exclusive of the H. pylori Core Genome include subsets of genes that appear to be linked with specific pathological outcomes

A total of 2,866 genes were detected from 122 H. pylori strains. Of these, 1,146 genes constituted the core genome shared by all isolates. There were 1,839 genes present in the isolates of the four disease groups, but not necessarily in all the isolates. The overlapping areas contain genes that are detected in multiple corresponding clinical outcome groups. Abbreviations: GC, gastric carcinoma; GU, peptic ulcer; CAG, chronic atrophic gastritis; CSG, chronic superficial gastritis.