Figure 3.

Functional classification of core genes in 122 H. pylori strains reveals predominant basic structure and metabolism genes as well as a group of genes with unknown functions

The functional classifications of 1,146 core genes were explored in the COG database. The X-axis denotes the functional category. The Y-axis represents the number of genes in each category. The detailed functions are represented in the right panel. Most core genes are involved in basic bacterial structure and metabolism. However, there was also a high proportion of functionally unknown genes, which could contain genes functioning in H. pylori pathogenesis pathways.