Table 4. Recurrent pathologic findings by organ/organ-system.
Organ/system | Organ Specific | Microthrombi | Endothelial Injury | TE disease | Vasculitis | Inflammation* | H/D compromise |
---|---|---|---|---|---|---|---|
n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | |
Upper airways+ | - | - | - | - | - | - | |
Lung | 132 (38.6) | 61 (17.8) | 47 (13.7) | 10 (2.9) | 21 (6.1) ** | 27 (7.9) | |
GI | - | 2/83 (2.4) | 2 (2.4) | - | - | - | |
Liver | - | - | 1/236 (.4) | 93 (39.4) | - | 59 (25.0) | |
Heart | - | - | 8/210 (3.8) | - | 37 (17.6) | - | |
Kidney | - | 55/276 (19.9) | 1 (0.4) | 2 (0.7) | - | - | |
CNS | - | 20/110 (18.2) | - | 9 (8.2) | - | 9 (8.2) | |
Hem-Lymph | - | - | - | 1/136 (0.7) | - | 7 (5.2) | |
Skin | - | 13/44 (29.5) | 1 (2.3) | - | 11 (25.0) | - | |
Placenta | - | - | - | - | 1 (5.3) | - |
GI- gastrointestinal, CNS- central nervous system, Hem-lymph- hematolymphoid, DAD- Diffuse alveolar damage, TE- thromboembolic, H/D-hemodynamic. +Trachea, pharynx, bronchial, mucosa.
* Possible cytopathic effect.
** Inflammation not related to Diffuse Alveolar Damage. Highlighted- most common abnormality by organ-system.