Fig 1. Schematic summary of patient enrollment, and subsequent, sampling, diagnostic procedures, and performance of RPA-LF evaluation in two scenarios.

A) Reference lab scenario: samples were obtained by highly trained field technician in Tumaco and processed in a reference center in Cali. In Cali samples were obtained and processed by an expert microbiologist. B) Field scenario: samples were obtained by trained community health workers (CHW), RPA-LF was processed by a non-expert field technician in Tumaco in primary health facility (PHF), and swabs were sent to reference center to be processed. C. Performance of RPA-LF test.