. Author manuscript; available in PMC: 2022 Apr 1.

Published in final edited form as: Circ Arrhythm Electrophysiol. 2021 Mar 16;14(4):e008751. doi: 10.1161/CIRCEP.120.008751

Table 4.

Immunology in Patients With and Without Recipient-to-Donor Atrio-Atrial Connections

	AAC^* (n=9) (LA^‡ mapping performed in 8/9 patients)	No ACC^* (n=13) (LA^‡ mapping performed)	No AAC^* evident (n=20) (LA^‡ mapping not performed)	p
DSAB^† present	0 (0%)	9 (69%)	8 (40%)	0.002^\|\|

Vasculopathy (+)	2 (22%)	8 (62%)	4 (20%)	0.07^\|\|

PRA^§ at transplantation (+)
Peak PRA^§ at transplantation	1/8 (12%)	3/12 (25%)	4/16 (25%)	ns
(continuous) (median/IQR)	0.00/1.00	0.00/1.00	0.00/6.00	ns
Data missing	1 (11%)	1 (8%)	4 (20%)	(0.15)^\|\|

Peak biopsy grade (1^st year)
Peak biopsy grade (>1 year)	1.00/2.00	1.00/2.00	2.00/3.00	ns
Biopsy Score	1.00/1.00	1.00/2.00	1.00/1.00	ns
(median/IQR)	0.23/0.13	0.12/0.33	0.19/0.44	ns

AAC=recipient-to-donor atrio-atrial connection

^†

DSAB=donor specific antibodies

^‡

LA=left atrium

^§

PRA=panel reactive antigen

^||

comparing patients with AAC to no AAC