Table 2:
PE (All Grades, n = 21) vs. PPE (n = 27) | Mild PE (n = 15) vs. PPE (n = 27) | |||||||
---|---|---|---|---|---|---|---|---|
AUC Analysis | At 95% Specificity | AUC Analysis | At 95% Specificity | |||||
AUC ± SE | P-value* | Sensitivity | Cutoff Value (µm) | AUC ± SE | P-value* | Sensitivity | Cutoff Value (µm) | |
Conventional (1.73 mm radius) RNFLT | 0.78 ± 0.07 | N/A | 0.33 | 159.3 | 0.70 ± 0.09 | N/A | 0.067 | 161.4 |
RNFL250 | 0.84 ± 0.06 | 0.42 | 0.48 | 369.7 | 0.80 ± 0.07 | < 0.0001 | 0.33 | 369.7 |
TRT250 | 0.85 ± 0.06 | 0.34 | 0.43 | 653.9 | 0.79 ± 0.07 | 0.34 | 0.20 | 657.9 |
MRW | 0.82 ± 0.06 | < 0.0001 | 0.43 | 645.7 | 0.76 ± 0.08 | < 0.0001 | 0.20 | 646.5 |
BMO Height | 0.90 ± 0.04 | < 0.0001 | 0.57 | −14.2 | 0.89 ± 0.05 | < 0.0001 | 0.53 | −14.2 |
PE = papilledema; PPE = pseudopapilledema; AUC = area under the curve; SE = standard error; RNFLT = retinal nerve fiber layer thickness; RNFL250 = RNFLT from BMO to 250 µm; TRT250 = total retinal thickness from BMO to 250 µm; MRW = minimum rim width; BMO = Bruch’s membrane opening
P-value comparing AUC to standard RNFL thickness AUC