Table A1: Distribution of custom retinal nerve fiber layer and total retinal thickness values for all eyes.
Conventional retinal nerve fiber layer thickness, custom retinal nerve fiber layer thickness, and custom total retinal thickness values for control, papilledema, and pseudopapilledema eyes. Papilledema and pseudopapilledema eyes are described as “better” or “worse” depending on which eye had a thicker conventional retinal nerve fiber layer (worse = thicker). In the present study, “better” papilledema eyes were compared to “worse” pseudopapilledema eyes in order to make the two groups more difficult to differentiate. Values for both eyes are included here to provide a more complete clinical picture.
| Retinal Nerve Fiber Layer Thickness Median (Interquartile Range), µm | Total Retinal Thickness Median (Interquartile Range), µm | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Conventiona l (1.73 mm radius) | BMO to 250 µm | 250 to 500 µm | 500 to 1000 µm | 1000 to 1500 µm | Within BMO | BMO to 250 µm | 250 to 500 µm | 500 to 1000 µm | 1000 to 1500 µm | |
| Control (n = 42) | 91.0 (86–96) | 168.6 (134–183) | 143 (125–156) | 105 (100–114) | 78.1 (76–83) | 201.7 (88–297) | 331.8 (297–374) | 330.6 (311–348) | 312.5 (298–323) | 293.7 (285–306) |
| PE (worse) (n = 21) | 231 (105–312) | 378.7 (309–456) | 267.7 (215–326) | 135.8 (121–193) | 87.8 (77–100) | 833.3 (670–1003) | 671.5 (573–735) | 503.1 (444–580) | 357.3 (338–423) | 301.1 (290–313) |
| PE (better) (n = 21) | 128.7 (102–207) | 306.2 (262–424) | 227.3 (205–342) | 130.5 (122–191) | 88.1 (82–103) | 710.2 (568–911) | 612 (517–771) | 461.8 (431–585) | 351.8 (336–416) | 297.4 (289–314) |
| Mild PE (worse) (n = 15) | 107.7 (104–151) | 321.1 (297–368) | 222 (194–267) | 123.5 (118–143) | 81 (75–88) | 706.1 (651–888) | 581.8 (538–645) | 460.1 (409–491) | 344.4 (330–356) | 290 (281–297) |
| Mild PE (better) (n = 15) | 109.9 (100–132) | 293.6 (260–377) | 218 (204–276) | 127.6 (120–147) | 85.6 (81–90) | 618.8 (516–786) | 529.8 (503–631) | 432.4 (425–498) | 341.1 (332–366) | 295.5 (285–299) |
| PPE (worse) (n = 27) | 102 (87–107) | 213 (177–262) | 162 (140–198) | 114.1 (100–124) | 79.4 (74–88) | 548.7 (396–703) | 459.1 (418–538) | 381.5 (356–410) | 322.8 (308–336) | 285.1 (274–293) |
| PPE (better) (n = 27) | 99.0 (91–105) | 212.2 (164–291) | 167.3 (150–200) | 116.7 (104–123) | 83.9 (74–88) | 564.4 (385–667) | 498.8 (411–542) | 390.5 (368–418) | 328 (315–342) | 293 (275–300) |
BMO = Bruch’s membrane opening; PE = papilledema; PPE = pseudopapilledema; worse = eye with thicker conventional retinal nerve fiber layer; better = eye with thinner conventional retinal nerve fiber layer