Table 1.
Patient characteristics of the entire study cohort before and after propensity-score matching
| Variables | Before matching | After matching | |||||
|---|---|---|---|---|---|---|---|
| Argatroban n = 39 |
UFH n = 465 |
SMD | Argatroban n = 39 |
UFH n = 78 |
SMD | p value | |
| Age, years | 55 (46; 61) | 53 (40; 62) | 0.197 | 55 (46; 61) | 56 (48; 63) | 0.096 | 0.538 |
| Female patients | 10 (26) | 138 (30) | 0.194 | 10 (26) | 27 (35) | 0.151 | 0.325 |
| BMI, kg/m2 | 27.7 (24.9; 34.0) | 27.8 (24.5; 33.0) | 0.006 | 27.7 (24.9; 34.0) | 29.2 (24.9; 33.2) | 0.095 | 0.675 |
| SOFA | 12.0 (10.0; 15.0) | 12.0 (9.0; 15.0) | 0.124 | 12.0 (10.0; 15.0) | 12.0 (9.0; 14.3) | 0.153 | 0.354 |
| ARDS subgroup | 0.549 | 0.284 | 0.816 | ||||
| I: pulmonary | 31 (79) | 281 (60) | – | 31 (79) | 60 (77) | – | |
| II: non-pulmonary | 5 (13) | 95 (20) | – | 5 (13) | 9 (11) | – | |
| III: post-trauma | 0 (0) | 43 (9) | – | 0 (0) | 2 (3) | – | |
| IV: mis-cellaneous | 3 (8) | 46 (10) | – | 3 (8) | 7 (9) | – | |
| Days of ventilation before ECMO | 1 (0; 2) | 1 (1;4) | 0.212 | 1 (0; 2) | 1 (0; 2) | 0.146 | 0.774 |
| Resuscitation before ECMO | 8 (21) | 74 (16) | 0.119 | 8 (21) | 15 (19) | 0.032 | 0.869 |
| Days on ECMO support | 11 (8; 16) | 8 (6; 14) | 0.349 | 11 (8; 16) | 10 (6; 16) | 0.086 | 0.303 |
Data are expressed as n (%), median (25. percentile; 75. percentile); miscellaneous includes drowning, pulmonary embolism, cystic fibrosis, and bridge to transplant; ARDS: acute respiratory distress syndrome; UFH: unfractionated heparin; SMD: standardized mean difference