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. 2021 Apr 19;2021:6634837. doi: 10.1155/2021/6634837

Figure 8.

Figure 8

Inhibition of MMP-3 and MMP-13 protein expression in IL-1β-induced SW1353 cells by total flavonoids of Rhizoma Drynariae (TFRD). Before stimulation with 10 ng/mL IL-1β for 12 h, cells were pretreated with 150, 300, or 600 μg/mL TFRD or 100 μmol/L dexamethasone (DEX) for 1 h. Subsequently, the supernatants of the cultured cells were collected, and MMP-1, MMP-3, and MMP-13 levels were measured by ELISA. The data are derived from three independent experiments and expressed as the mean ± standard deviation (∗p < 0.01 compared with the control group; #p < 0.05 compared with the IL-1β-treated group).