Table 2.
Vinegar/TMP preconditioning preserves the myocardial homogenate ferric reducing antioxidant potentiality and the activities of antioxidant enzymes and reduced the levels of lipid peroxidation in the myocardium against A/R injury.
| Groups | FRAP (mmol Fe2+/l) | SOD activity (U/g tissue) | GPx activity (U/g tissue) | CAT activity (U/g tissue) | MDA content (nmol/g tissue) |
|---|---|---|---|---|---|
| Control | 5.11 ± 0.20 | 86.32 ± 4.22 | 19.52 ± 1.46 | 14.68 ± 1.25 | 29.06 ± 1.83 |
| A/R | 1.42 ± 0.04a | 20.82 ± 1.61a | 4.83 ± 0.51a | 6.35 ± 0.52a | 140.28 ± 7.52a |
| Vinegar+A/R | 4.06 ± 0.23b | 51.61 ± 2.62b | 13.06 ± 1.35b | 10.28 ± 0.82b | 82.31 ± 5.06b |
| TMP+A/R | 4.35 ± 0.22b | 56.28 ± 2.81b | 15.20 ± 1.38b | 11.06 ± 0.76b | 78.62 ± 4.91b |
| Vinegar+A/R+pAD/VDAC1 | 1.93 ± 0.06c | 25.12 ± 1.85c | 6.62 ± 0.60c | 7.21 ± 0.54c | 135.20 ± 7.08c |
| TMP+A/R+pAD/VDAC1 | 2.15 ± 0.05d | 27.32 ± 1.66d | 6.91 ± 0.58d | 7.02 ± 0.53d | 132.61 ± 7.63d |
| Vinegar+A/R+Atr | 1.71 ± 0.05c | 22.08 ± 1.58c | 4.51 ± 0.61c | 5.86 ± 0.55c | 146.65 ± 8.02c |
| TMP+A/R+Atr | 1.86 ± 0.06d | 21.39 ± 1.62d | 4.92 ± 0.57d | 5.98 ± 0.58d | 143.28 ± 7.31d |
Data were presented as the mean ± SEM for five individual experiments. aP < 0.01 vs. the control group. bP < 0.01 vs. the A/R group. cP < 0.01 vs. the vinegar+A/R group. dP < 0.01 vs. the TMP+A/R group.