Table 2.
Effect of factors on overall survival in lung cancer patients in the univariate and multivariate Cox regression model.
| Factors | Univariate∗ | Multivariate∗,†,‡ | ||
|---|---|---|---|---|
| HR (95% CI) | p | HR (95% CI)∗ | p | |
| Age (<48/≥48) | 2.69 (0.85-8.49) | 0.091 | — | — |
| Gender (male/female) | 1.34 (0.85-2.12) | 0.206 | — | — |
| Differentiation (poor/well, moderate) | 1.12 (0.76-1.65) | 0.563 | — | — |
| Lymph node invasion (present/absent) | 0.49 (0.33-0.71) | 0.000 | — | — |
| Clinical stage (III-IV/I-II) | 2.85 (1.92-4.22) | 0.000 | 2.71 (1.82-4.02) | 0.000 |
| Brf1 (high/low) | 0.55 (0.36-0.84) | 0.006 | 0.60 (0.39-0.93) | 0.021 |
∗Hazard ratios and p values were obtained from Cox proportional hazards regression. All statistical tests were two-sided. †For the multivariate model, HR and p values were shown for the final set of stepwise selected variables only. ‡The parameters with p value less than 0.05 in the univariate were included in the multivariate Cox analysis using SPSS 20.0.